Behavior of Male and Female C57BL/6J Mice Is More Consistent with Repeated Trials in the Elevated Zero Maze than in the Elevated Plus Maze

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Behavior of Male and Female C57BL/6J Mice Is More Consistent with Repeated Trials in the Elevated Zero Maze than in the Elevated Plus Maze

The elevated plus maze (EPM) and elevated zero maze (EZM) are behavioral tests that are widely employed to assess anxiety-like behaviors in rats and mice following experimental manipulations, or to test the effects of pharmacological agents. Both tests are based on approach/avoidance conflict, with rodents perceived as "less anxious" being more willing to explore the brighter, open and elevated...

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ژورنال

عنوان ژورنال: Frontiers in Behavioral Neuroscience

سال: 2017

ISSN: 1662-5153

DOI: 10.3389/fnbeh.2017.00013